• Read more about A022104

Short Title: JANUS

This phase II trial compares the effect of irinotecan versus oxaliplatin after long-course chemoradiation in patients with stage II-III rectal cancer. Combination chemotherapy drugs, such as FOLFIRINOX (fluorouracil, irinotecan, leucovorin, and oxaliplatin), FOLFOX (leucovorin, fluorouracil, oxaliplatin, and irinotecan), and CAPOX (capecitabin and oxaliplatin) work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

Study Number:

A022104

Study Status:

Enrolling

Treatment Agent:

Capecitabine, 5-fluorouracil, Leucovorin calcium, Irinotecan, Oxaliplatin

Resources and Links

National Clinical Trial Identified Number: NCT05610163

Disease:

• Locally Advanced Rectal Carcinoma

Study Phase:

II

researchcancer@cooperhealth.edu

Index Extra:

GI, gastro, rectal

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Physician Name:

• Jamin C. Morrison, MD, MBA

Department:

• Hematology and Medical Oncology